FRANKFURT, Germany-(BUSINESS WIRE)–Merz Therapeutics, mtsogoleri pankhani ya neurotoxins ndi bizinesi yomwe ili pansi pa Merz Group, ndi Teijin Pharma Limited, kampani yayikulu yabizinesi yazaumoyo ya Teijin Group, adalengeza lero kuti Teijin Pharmaceuticals yapambana Zowonjezera. chivomerezo chochokera ku Unduna wa Zaumoyo, Ntchito ndi Umoyo ku Japan (MHLW) kuti agwiritse ntchito Xeomin® (incobotulinumtoxinA) mu mayunitsi 50, 100 kapena 200 a jakisoni wa intramuscular pochiza minyewa ya m'munsi.
Kutsika kwa mitsempha ya m'munsi ndi chizindikiro cha matenda apamwamba a neuron, omwe amawonekera makamaka ndi kuwonjezeka kwa minofu ya miyendo ndi chisangalalo chochuluka cha kutambasula reflex monga sequelae ya sitiroko.Zizindikiro zazikulu zimakhala zovuta kuyenda bwino komanso chiopsezo chowonjezeka cha kugwa chifukwa cha thunthu losakhazikika, zovuta kapena zolepheretsa zochitika pamoyo watsiku ndi tsiku.Kuchiza kwanthawi zonse kwa kukomoka kwa miyendo kumaphatikizapo kukonzanso thupi komanso kugwiritsa ntchito mankhwala opumitsa minofu yapakamwa kapena otsekereza neuromuscular, monga mtundu wa poizoni wa botulinum A.
Stefan Brinkmann, CEO wa Merz Therapeutics, adati: "Chivomerezo chotalikirachi ndi gawo lofunikira kwambiri ku Merz Therapeutics ndipo ndi zotsatira za mgwirizano wathu wapamtima ndi Teijin Pharmaceuticals.Tikukhulupirira kuti anzathu awonetsa bwino izi kwa madokotala ndi odwala aku Japan. ”
Dr. Stefan Albrecht, Wachiwiri kwa Wachiwiri kwa Purezidenti wa Global R&D, Merz Therapeutics: "Kukula kwa zilembo ku Japan ndi chitsanzo china chodziwika bwino cha zabwino zomwe Xeomin ® imapereka kwa odwala ambiri omwe ali ndi vuto la poststroke.Madokotala tsopano atha kusankha kuchiza m'munsi ndi kumtunda kwa spasticity, kapena akhoza kusinthasintha momwe angafunikire Gwiritsani ntchito mlingo umodzi mosamala.Ndife onyadira kuchita izi, makamaka mgwirizano wabwino kwambiri ndi mnzathu Teijin. ”
Purezidenti wa Teijin Pharmaceutical, Ichiro Watanabe, adati: "Teijin Pharmaceutical imapereka mankhwala osiyanasiyana, kuphatikizapo chithandizo cha osteoporosis ndi zipangizo zachipatala, monga phokoso la phokoso lomwe limathandizira kuchiritsa fracture kwa odwala omwe ali ndi matenda a musculoskeletal.Poyankha kusintha kwa chiwerengero cha anthu ndi kuwonjezeka kwa chidziwitso cha thanzi , Tikuyambitsa mankhwala atsopano ogwira ntchito ndi zothetsera, kuphatikizapo kukwaniritsidwa kwa anthu okhazikika.Mankhwala a Teijin Pharmaceuticals akupitiriza kuthandizira kukonza moyo wabwino (QOL) wa odwala popereka njira zatsopano zothandizira matenda omwe ali ndi zosowa zosakwanira.”
Xeomin® imathandizira bwino mathero a mitsempha ya cholinergic mwa kufooketsa kukangana kwa minofu yodzifunira, ndikuchepetsa kupsinjika kwa minofu poletsa kutulutsa kwa neurotransmitter yotchedwa acetylcholine.Neurotoxin yoyeretsedwa kwambiri ndiyo yokhayo yomwe imagwira ntchito mu Xeomin®.Zimapangidwa ndi kuchotsa mapuloteni ovuta kuchokera ku mtundu wa A botulinum poizoni wopangidwa ndi Clostridium botulinum pogwiritsa ntchito teknoloji yoyeretsa yopangidwa ndi Merz Pharma GmbH & Co. KGaA.Kuperewera kwa mapuloteni ovuta kumapangitsa Xeomin® kuchepetsa kupanga ma antibodies omwe amatha kuchepetsa mphamvu.Kusintha kwakukulu pamlingo wa plantar flexor modified ashworth scale (MAS) kunachitika muyeso lachipatala la gawo lachitatu ku Japan.
Xeomin® imafalitsidwa ndi Merz Pharmaceuticals GmbH m'maiko opitilira 70 ndipo imagwiritsidwa ntchito pochiza odwala omwe ali ndi minyewa yam'mwamba, khomo lachiberekero dystonia, blepharospasm kapena malovu ochulukirapo.Kampani ya Teijin Pharmaceuticals inasaina layisensi yokhayo komanso mgwirizano wapagulu wa Xeomin® ku Japan ndi Merz mu 2017, ndipo idayamba kugulitsa Xeomin® mu Disembala 2020 italandira chilolezo kuchokera ku Unduna wa Zaumoyo, Ntchito ndi Umoyo (MHLW) waku Japan.Kutengera kuyeserera kwachipatala kwa Merz's Phase III ku Japan, zivomerezo zowonjezera zomwe zangopezedwa kumene zasintha zina mwazovomerezeka.
Nthawi zambiri, kwa akulu, Xeomin® iyenera kubayidwa muminofu yambiri yolimba.* Mlingo wochuluka pa makonzedwe onse ndi mayunitsi a 400, koma ayenera kuchepetsedwa moyenerera mpaka mlingo wocheperako malinga ndi mtundu ndi chiwerengero cha minofu ya tonic.Ngati zotsatira za mlingo wapitawo zichepa, kubwereza Mlingo amaloledwa.Mlingo uyenera kukhala masabata 12 kapena kupitilira apo, koma ukhoza kufupikitsidwa mpaka milungu 10 kutengera ndi zizindikiro.
* Myotonic: gastrocnemius (mutu wapakati, mutu wotsatira), soleus, posterior tibialis, flexor digitorum longus, etc.
Merz Therapeutics ndi bizinesi ya Merz Pharmaceuticals GmbH yodzipereka kukonza miyoyo ya odwala padziko lonse lapansi.Ndi kafukufuku wake wosalekeza, chitukuko ndi chikhalidwe chatsopano, Merz Therapeutics imayesetsa kukwaniritsa zosowa za odwala ndikupeza zotsatira zabwino.Merz Therapeutics ikufuna kukwaniritsa zosowa zapadera za anthu omwe akudwala matenda oyenda, matenda amisempha, matenda a chiwindi, ndi zina zaumoyo zomwe zimakhudza kwambiri moyo wa odwala.Merz Therapeutics ili ku Frankfurt, Germany, ndi maofesi oimira mayiko oposa 90, ndi nthambi ya ku North America ku Raleigh, North Carolina.Merz Pharmaceuticals GmbH ndi gawo la Merz Group, kampani yomwe ili ndi mabanja mwachinsinsi yomwe yadzipereka kupanga zatsopano zomwe zimakwaniritsa zosowa za odwala ndi makasitomala kwazaka zopitilira 110.
Teijin (Tokyo Stock Exchange code: 3401) ndi gulu lapadziko lonse lapansi loyendetsedwa ndi ukadaulo lomwe limapereka mayankho apamwamba pazachilengedwe;chitetezo, chitetezo, ndi kuchepetsa masoka;komanso kusintha kwa chiwerengero cha anthu komanso kuwonjezeka kwa chidziwitso cha thanzi.Teijin idakhazikitsidwa koyamba mu 1918 ngati woyamba kupanga ma rayon ku Japan, ndipo tsopano yapanga bizinesi yapadera yomwe imakhudza magawo atatu abizinesi: zida zogwira ntchito kwambiri kuphatikiza ma aramid, kaboni fiber ndi zida zophatikizika, komanso utomoni ndi pulasitiki, Mafilimu. , poliyesitala CHIKWANGWANI ndi processing mankhwala;chithandizo chamankhwala, kuphatikizapo mankhwala ndi zipangizo zapakhomo za mafupa / olowa, kupuma, ndi matenda a mtima / kagayidwe kachakudya, unamwino ndi chisamaliro chisanachitike;ndi IT, kuphatikiza mayankho azachipatala, makampani ndi B2B pamakina aboma, komanso mapulogalamu opakidwa ndi mautumiki apaintaneti a B2C pazosangalatsa zama digito.Monga tafotokozera m'mawu akuti "Human Chemistry, Human Solutions", Teijin akudzipereka kwambiri kwa omwe akukhudzidwa nawo ndipo akufuna kukhala kampani yomwe imathandizira anthu am'tsogolo.Gululi limapangidwa ndi makampani opitilira 170 ndipo ali ndi antchito pafupifupi 20,000 m'maiko / zigawo 20 padziko lonse lapansi.M'chaka chandalama chomwe chimatha pa Marichi 31, 2021, Teijin adalengeza kugulitsa kophatikizana kwa yen biliyoni 836.5 ($ 7.7 biliyoni) ndi chuma chonse cha yen biliyoni 1.036.4 ($ 9.5 biliyoni).
Nthawi yotumiza: Sep-10-2021