Mark Gurarie ndi wolemba pawokha, mkonzi komanso mphunzitsi wanthawi yochepa pantchito yolemba pa yunivesite ya George Washington.
Anita Chandrasekaran, MD, Master of Public Health, wotsimikiziridwa ndi Board of Internal Medicine ndi Rheumatology, panopa amagwira ntchito ngati rheumatologist ku Hartford Healthcare Medical Group ku Connecticut.
Gel-One (hyaluronate yolumikizidwa pamtanda) ndi njira yochizira matenda a mafupa a bondo (OA).Iyi ndi jekeseni yomwe imathandiza kuthetsa ululu wokhudzana ndi ululu.
Amachokera ku puloteni (hyaluronic acid) yotengedwa muzisa kapena zisa.Thupi la munthu mwachibadwa limapanga puloteni iyi kuti ipangitse mafuta m'malo olumikizirana mafupa.Ntchito yake ndi kubwezeretsa mlingo wa mapuloteni.
Gel-One idavomerezedwa koyamba ndi US Food and Drug Administration (FDA) ku 2001. Inangoyesedwa mu mayesero a zachipatala ndipo inatsimikizira kuti ndi yothandiza kuchepetsa ululu kwa masabata a 13, koma mapeto ena, kuphatikizapo kuuma Ndi thupi. ntchito, palibe kusiyana kwa ziwerengero komwe kunapezeka ndi placebo.
Palibe mankhwala athunthu a OA.Chithandizochi chimangochitika pambuyo poyesa njira zina zowongolera (monga kumwa mankhwala kapena kusintha moyo).
Monga mankhwala aliwonse, jekeseni wa Gel-One alibe zotsatirapo ndi zoopsa.Ngati muli ndi OA, ndikofunikira kudziwa zambiri momwe mungathere za dongosolo lanu lamankhwala.
Gel-One ndi yoyenera kwa OA ya bondo, yomwe imadziwika ndi kutayika kwa mgwirizano, zomwe zimayambitsa kupweteka.OA ndi matenda a nyamakazi omwe amapezeka kwambiri, ndipo ngakhale amakhudza aliyense, amapezeka kwambiri mwa anthu azaka zopitilira 65.
Choyamba, pamene mankhwala ena (monga kumwa mankhwala osagwiritsa ntchito steroidal anti-inflammatory (NSAID) kapena physiotherapy) sakugwira ntchito, Gel-One idzayesedwa.Popeza OA ndi matenda opita patsogolo komanso osachiritsika, ngakhale kuti opaleshoni ingakhale njira yabwino, kuchiza kumatanthauza kuchepetsa zizindikiro.Jakisoniyu akuyimira mankhwala owonjezera olimba.
Musanaganizire jekeseni wa Gel-One ngati chithandizo, kuyezetsa koyenera kwa OA ndikofunikira.Kodi mungawunike bwanji mkhalidwewu?Ichi ndi chidule chachangu:
Kambiranani mankhwala onse, zowonjezera, ndi mavitamini omwe mukumwa ndi dokotala wanu.Ngakhale mankhwala ena amakhala pachiwopsezo chochepa cha kuyanjana, mankhwala ena amatha kukhala otsutsana kwathunthu kapena mwachangu kuti muganizire mosamala ngati mapindu ndi zovulaza za chithandizo ndizokulirapo kuposa momwe mukumvera.
Zochokera ku hyaluronic acid zomwe zimagulitsidwa pansi pa mayina monga Restylane, Juvéderm ndi Perlane ndizodzaza kumaso zomwe zimagwiritsidwa ntchito kusalaza makwinya kapena milomo yochuluka.Mofanana ndi mafupa, milingo ya hyaluronic acid imachepa ndi zaka, zomwe zimapangitsa kuti khungu likhale lolimba.Pobaya izi kumaso, khungu limakhala lolimba.
Kuphatikiza apo, madokotala atha kugwiritsa ntchito topical hyaluronic acid ngati njira yochizira kutupa kwa chingamu kwanthawi yayitali.Kuphatikiza pa mankhwala ena, amathandizanso kuchepetsa kutupa m'maderawa ndikuthandizira kuchiza gingivitis, periodontitis ndi mavuto ena.
Majekeseni a Gel-One amangoperekedwa ndi ogwira ntchito zachipatala m'makonzedwe a chipatala, ndipo monga tafotokozera pamwambapa, sikulimbikitsidwa kuchita chithandizo chamtunduwu kangapo kamodzi pa bondo.Imadzazidwa mu syringe yagalasi yoyikiratu, yodzaza ndi mamililita atatu (mL) a yankho, omwe ali ndi mamiligalamu 30 (mg) a asidi a hyaluronic.
Seigaku Corporation, yomwe imapanga Gel-One, ndipo FDA ikugogomezera kuti sikuvomerezeka kutenga kangapo kapena kusintha mankhwala.Komabe, ngati simukutsimikiza, onetsetsani kuti mukukambirana za mlingo woyenera ndi dokotala wanu.
Ngakhale kasamalidwe ndi kusungirako kumadalira wothandizira zaumoyo wanu, ndikofunikira kumvetsetsa momwe izi ziyenera kuonekera.Kugwiritsa ntchito bwino Gel-One kuli motere:
Zotsatira zoyipa za jekeseni wa Gel-One zimatha kuthetsa;komabe, muyenera kudziwitsa wothandizira zaumoyo wanu ngati mavutowa akupitilira kapena kuchitika.Zikuphatikizapo:
Mukatha kulandira chithandizo, chonde tcherani khutu momwe mukumvera.Ngati mukuganiza kuti mukufuna thandizo, chonde musazengereze kupempha thandizo.
Zowopsa za Gel-One ndizosowa ndipo zambiri zimayamba chifukwa cha kusagwirizana ndi mankhwala.Ngati mukukumana ndi izi, chonde funsani thandizo mwamsanga:
Chifukwa chomwe Gel-One imalekerera nthawi zambiri ndikuti mankhwalawa amaperekedwa ndi wothandizira zaumoyo, motero amachepetsa mwayi wowonjezera.Popeza nthawi zambiri samapatsidwa kangapo (makamaka pa bondo lomwelo), kuthekera kwa kugwirizana koyipa pakati pa mankhwalawa ndi mankhwala ena omwe mukuwatenga ndi otsika kwambiri.
Komabe, ndikofunikira kuti ngati khungu lanu latsukidwa ndi quaternary ammonium disinfectant, musalandire jakisoni wa Gel-One.Mankhwala angakhudzidwe ndi njira zoterezi.
Casale M, Moffa A, Vella P, etc. Hyaluronic acid: tsogolo la mano.kuwunika kwadongosolo.Int J Immunopathol Pharmacol.2016;29(4):572-582.
Nthawi yotumiza: Oct-19-2021